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thanks for your cooperationThe Change-Activation-Sustaining model: assisting patients with cancer to identify their distress and mobilize action.
People with cancer often experience unmet psychosocial needs, including distress, and even complete emotional breakdown. Nurses are uniquely placed to respond to these needs but are generally unsure about how best to respond to distress in patients with cancer. The aim of this paper is to investigate the psychometric properties of the Change-Activation-Sustaining (CASS) model for the purposes of developing a suitable distress assessment tool for cancer patients. A comparative study design was used to determine the psychometric properties of the CASS model. The CASS model was tested in patients with breast cancer, using a questionnaire comprised of the CASS subscales. The questionnaire was completed by the patient and the nurse. Test-retest reliability was assessed by having the patient complete the questionnaire again at a 5-day interval. The 12-item CASS model yielded acceptable internal consistency (alpha = 0.81), and the results indicated satisfactory test-retest reliability (rho = 0.71) in measuring the patient’s sense of distress. A brief distress assessment tool can be used with confidence by nurses to identify and address emotional distress in cancer patients.Occurrence of the enteropathogenic bacterium, Shigella sonnei, in the flagellar apparatus of a human intestinal epithelial cell line.
The human intestinal epithelial cell line, Caco-2, was found to be permissive to the replication of a human strain of Shigella sonnei. Shigella were observed in the flagellar apparatus of Caco-2 cells. In addition, incorporation of [3H]thymidine was seen only in the specific chromosomal region of the infected cells, and enlarged nuclei were also observed. The infected cells showed an elongated shape which may be the consequence of the central position of the bacteria in the flagellar apparatus. The results